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The early divergence of the MACE occurrence curves between the SEMA and placebo groups23 suggests that SEMA may have been directly involved in the SELECT study results through its effects on angiogenesis, reduction of oxidative stress and inflammation, and anti-atherogenic actions derived from GLP-1R activation that promote endothelial function and cell survival7 (Fig
Group 4: Complete bilateral clefts
Individual responses to the starting dose vary enormously
This dual modulation contributes to better HbA1c (long-term sugar) control and fewer glucose spikes
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