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Overall, preclinical studies have shown that GLP-1RA reduces alcohol consumption, reduces motivation to drink alcohol, and prevents alcohol relapse, potentially reducing alcohol-induced reward [91]

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In this study, we sought to investigate the potential protective effects and associated molecular mechanisms of sulforaphane in an in vivo Parkinsons disease (PD) model, based on rotenone-mediated neurotoxicity

ROS induces the activation of mitogen activated kinase (MAPK), downregulates the phosphorylation level of extracellular regulatory protein kinase (p-ERK), upregulates activated nuclear transcription factor (NF-KB), activates autophagy pathway, and leads to apoptosis of retinal photoreceptor cells