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(2) Pathophysiology in ASD: ASD-associated disruptions include impaired electron transport chain (ETC) activityparticularly Complex I and IVleading to reduced ATP, increased ROS, and release of mitochondrial DAMPs (e.g., mtDNA)

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D., Zheng, Y., Wang, J

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MetS was defined as 3/5 cardiac risk factors: elevated waist circumference

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10.1006/bbrc.1999.1060

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