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Hypertension and metabolic syndrome together lead to more cases of left ventricular hypertrophy, microalbuminuria, increased intima-media thickness, and hypertensive retinopathy (115)
Current evidence suggests these medications do not directly cause clinically significant bone loss, though the substantial weight reduction they produce may indirectly influence bone metabolism
Gout Gout patients with diabetes, hypertension, and obesity see increased flares during rapid weight loss (common with GLP-1 or surgery), due to changes in uric acid
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