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Wegovy (semaglutide 2.4) and Zepbound (tirzepatide) are recent breakthroughs, enabling average weight losses of 1520% in clinical trials

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(3) removing a 20 amino acid R protection group at the N end of the main chain and coupling residual amino acids of the main chain in sequence according to a peptide sequence to obtain semaglutide full-protection peptide resin, wherein dipeptide fragments are selected as 18 -19 amino acids at the N end and 1 -2 amino acids at the N end