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These findings are not surprising, Mir Ali, MD, a bariatric surgeon, bariatric medicine specialist and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, told Medical News Today

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Higher GBB levels were also associated with increased risk ofand poorer survival frommajor cardiovascular events (death, myocardial infarction, or stroke), but only when TMAO levels were also elevated.14 Continuing along the carnitine metabolism pathway to the liver, individual genetic variation may play a role in elevated TMAO levels by increasing conversion of TMA to TMAO by the enzyme flavin-containing monooxygenase 3 (FMO3)