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Mast cells are now thought to also play a pathogenic role in the condition.[ref] Researchers have found that the average prostaglandin D2 levels (an indicator of mast cell activation) are higher in people with rheumatoid arthritis than in healthy controls.[ref] Related article : Rheumatoid arthritis genes Mast cells may play a role in obesity and diabetes: It has been known for a while that obesity is linked to increased systemic inflammation
What's actually in development Beyond the established options there is an active pipeline of experimental drugs: the kind going through registered, regulator-supervised human trials, with published or company-reported data anyone can check
doi: 10.1016/j.mam.2008.08.004 16 Bani YounesM.AlshawabkehA
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