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Nevertheless, its overall safety profile remains acceptable, with no severe adverse events reported thus far
In obesity-related HFpEF, where inflammation and metabolic dysfunction sit at the center of the disease, semaglutide was a natural fit. So, while weight loss across the board was anticipated (about 8% to 9% of body weight compared to placebo), the results this team found intriguing were semaglutides stratum-dependent ability to reduce frailty burden (strata = less frail, more frail, most frail)
[8] demonstrated that the incretin effect is impaired in patients with T2D
Antioxidants 12, 658
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