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Methylmalonyl-CoA Mutase : Converts methylmalonyl-CoA into succinyl-CoA in the Krebs cycle, supporting neuronal energy metabolism

Research published in the British Journal of Pharmacology demonstrated that molecular conjugation of B12 (specifically the corrin ring structure found in cyanocobalamin) with GLP-1 receptor agonists produced a compound that was not as readily absorbed into the brainstem areas responsible for triggering nausea

PLOS ONE 9, e102196.CrossRefGoogle Scholar -oxidation and promotes glucose metabolism

GLP-1RA such as dulaglutide or semaglutide are currently chosen for the control of T2DM in patients with cardiovascular risk factors [93]