Johnson JA, El Barbary A, Kornguth SE, Brugge JF, Siegel FL
To increase comparability between treatment groups, propensity score matching was performed using demographic features, body mass index (BMI), glycated hemoglobin (HbA1c), medical history, co-existing treatments, healthcare utilization, and results of laboratory investigations
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Studies suggest lactic acid from these delivery systems may modulate macrophage infiltration and upregulate TGF- expression, potentially facilitating endogenous collagen regeneration and sustained tissue remodeling