The title slide had a photo of a Ken doll with a syringe pointed at its forehead
Toxicology Findings Repeated-dose toxicity studies in rats, dogs, and mice for up to 6 weeks across doses from 6 mcg/kg to 20 mg/kg via various routes showed excellent tolerance

Check with your doctor immediately if any of the following side effects occur: More common Stomach pain Less common Difficulty in breathing or swallowing fast heartbeat gaseous stomach pain heartburn recurrent fever skin itching, rash, or redness stomach fullness swelling of the face, throat, or tongue vomiting yellow eyes or skin Incidence not known Anxiety bloating blurred vision chest tightness chills cold sweats confusion constipation cool, pale skin cough darkened urine depression dizziness fast heartbeat fever indigestion large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs loss of appetite nausea nervousness pains in the stomach, side, or abdomen, possibly radiating to the back puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue Shakiness unusual tiredness or weakness Some side effects may occur that usually do not need medical attention

Fasting-refeeding assays Age-synchronized worms were cultured on either experimental or control RNAi plates until Day 1 of adulthood