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Increased Energy Expenditure: GLP-1 RAs may activate sympathetic pathways in the hypothalamus (specifically the dorsomedial and ventromedial nuclei) that increase thermogenic activity in brown adipose tissue (BAT), contributing to increased energy expenditure and weight loss

In addiction treatment settings specifically, patients have generally tolerated the medications well, and clinicians have reported no unexpected or severe adverse effects

Retinoids may go back in tonight at half their usual dose if your skin feels fully recovered

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