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A recent study showed that long-term duloxetine use could cause significant cardiovascular problems in older individuals (aged 7079 years), particularly those who already have cardiovascular disease [125]

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Under normal conditions, PTEN-induced putative kinase 1 (PINK1) is continuously degraded by presenilin-associated rhomboid-like protein (PARL)

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Molecules 24:1211 Sang Q, Sun D, Chen Z, Zhao W (2018) NGF and PI3K/Akt signaling participate in the ventral motor neuronal protection of curcumin in sciatic nerve injury rat models

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One study published in the European Journal of Applied Physiology observed 83 people over a period of 12 weeks as they practiced progressive overload on a series of arm strengthening exercises gradually increasing the weight and number of repetitions of exercises

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