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Consider sedating antihistamine at bedtime if sleep is affected
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Specifically, these mechanisms of action cover multiple aspects, such as activation of the cAMP-PKA signaling pathway, inhibition of pro-inflammatory cytokine release, and also activation of the AMPK signaling pathway, promoting the expression of anti-inflammatory genes, and regulation of macrophage function [26]
Rational treatment of chemotherapy-induced peripheral neuropathy with capsaicin 8% patch: from pain relief towards disease modification
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