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doi: 10.1186/s12936-022-04166-x 80 HimmelTHarlJPfannerSNedorostNNowotnyNWeissenbckH
PubMed laboratory research record [PMID: 11833448] PubMed record related to this compound for laboratory literature review
CJC-1295 and Somatotroph Biology The GHRH-receptor signalling pathway activated by CJC-1295 stimulates adenylate cyclase, increasing intracellular cAMP and engaging PKA-linked transcriptional regulation of the GH gene in somatotroph cells with in vivo research confirming increased pituitary RNA, GH mRNA, and somatotroph cell number following administration, establishing that GHRH-class secretagogues act on multiple levels of GH axis biology beyond simple acute secretion
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