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After the clinical observation of phenotypes attributable to PFIC, current research techniques enable the isolation of novel variants related to known genes or variants in other genes that determine known or new cholestatic intrahepatic phenotypes

Before-and-after results typically emerge gradually, reflecting ongoing processes such as collagen and elastin remodeling, improved resilience, and enhanced tissue function rather than immediate cosmetic alteration

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The efficacy of skin care products containing glutathione in delivering skin lightening in Indonesian women