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P53 phosphorylation at Ser15 was confirmed to enhance the affinity for both FOXO4 and FOXO4-DRI, providing a structural explanation for FOXO4-DRIs preferential engagement with the hyperphosphorylated p53 that characterises senescent cells
If youve heard anything about its potential side effects (such as headaches, swelling, tingling, or facial redness), that info is likely anecdotal and not based on studies
So, the scientists went looking for cold-blooded animals instead
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