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The Spanish Ketogenic Mediterranean Diet study showed 14.47 kilograms of loss in 12 weeks, which is significant but generally less than what GLP-1 medications produce over similar timeframes in clinical trials

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Adv Ther 36: 1190-1199

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These effects tend to be most pronounced in the early weeks of treatment and during each dose increase, which aligns with what many users report about temporary dips in sexual interest that coincide with their tirzepatide dosing schedule

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Effect of endoscopic sleeve gastroplasty on gastric emptying, motility and hormones: a comparative prospective study

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