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Some physicians prescribe it longer, and research supports extended use in certain cases, but the fundamental problem remains: phentermine is fighting your biology with a blunt instrument, and your biology eventually fights back

For health-related QoL, the model includes a baseline QoL and uses decrements associated with micro- and macrovascular complications and obesity, as well as age, sex and diabetes duration (not used in this analysis) (Table S7 in Online Resource 1)

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