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As more generics enter the market, prices are expected to decrease further
Additive effects on weight loss were similarly demonstrated in the Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes Mellitus (SUSTAIN-9) and Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10) trials [103,104]
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semaglutide is the only one approved for obesity treatment Type 2 diabetes with cardiovascular risk Semaglutide Proven 20% MACE reduction in SELECT (obesity) and 26% in SUSTAIN 6 (T2D), while exenatide only achieved non-inferiority in EXSCEL Budget-conscious diabetes treatment Exenatide Lower cost and generic availability make exenatide accessible when newer agents are unaffordable or not covered by formulary Oral medication preference Semaglutide Rybelsus (oral semaglutide) offers injection-free GLP-1 therapy
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