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For example, alphavbeta 3 (v-3) integrin receptor adhesions and invasion have been demonstrated to be inhibited by cyclic RGD-functionalized solid lipid NP (RGD-SLN), which is overexpressed in invasive TNBC tumours (120)

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Cell Death Differ (2015) 22:37788

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These results all encourage a conclusion that LASSS treatment (at 1:8000 ratio to HGF) may enhance the c-met binding-affinity of HGF without disturbing HGF-c-Met signaling and that this enhancement occurs through a mechanism that is unrelated to prevention of HGF nitration

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& Tremblay, M

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