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The calcium-sensing receptor (CaSR) on somatostatin-producing D-cells in the stomach and hypothalamus responds to acute rises in ionized calcium by increasing somatostatin secretion [13]

This makes PT-141 one of the few peptides on this list with actual FDA approval in a specific context, though research-grade PT-141 is a separate product from the pharmaceutical version

One study explained that while the patient followed current guidelines, shortly prior to extubation, the patient developed large-volume emesis with contents consistent with food the patient reported eating several days prior (Beam and Hunter Guevara 2023)

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