tirzepatide 2.5 mg weight loss data Efficacy and safety of for treatment of overweight or obesity. A systematic review and meta-analysis Tirzepatide Dosing Chart 2026: 2.5-15

By reducing your appetite, they make you eat less

Bloating, Gas, and Reflux/Heartburn Shrink meal size , eat slowly, and avoid lying down for 23 hours after meals

Some populations are more prone to sickness with GLP-1 drugs

Research has linked prolonged PPI use to: Nutrient deficiencies (magnesium, calcium, iron, vitamin B12) (5) Increased risk of bone fractures and osteoporosis (6) Gut dysbiosis and increased risk of SIBO (7) Low stomach acid (which has been associated with leaky gut and autoimmune conditions) Higher susceptibility to infections Potential kidney and cardiovascular concerns (8, 9) Increased risk of cancer (10) Increased risk of inflammatory bowel disease (IBD) And, of course, PPIs do not address the root cause of reflux