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Enhanced NO Stability - Once NO is produced, glutathione acts as a powerful protector against oxidative damage

GSH can react with a wide range of molecules, making it an effective antioxidant at detoxifying many of the diverse reactive electrophilic components of CS

The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model

The table below outlines key differences in mechanism, duration, side effect profiles, and clinical evidence that should inform your provider discussion