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Deze ontsteking ontstaat doordat vetweefsel signalen afgeeft die het immuunsysteem licht activeren
Currently, there are three FDA-approved oral GLP-1s on the market in the US: Rybelsus, which is approved for type 2 diabetes, the Wegovy pill, which is approved for weight loss, and Foundayo, which is also approved for weight loss
High body mass index (BMI) has been shown to increase joint inflammation, exacerbating pain
Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times
