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Metal complex catalysis in living biological systems
For biosynthesis, it seems the only strategy to prolong the half-life is a ligand fused with a terminal albumin or Fc domain, whose critical points are length and location
2020 (ASCO guideline): Based on the above evidence, the American Society of Clinical Oncology recommended in 2020 that clinicians DISCOURAGE use of acetyl-L-carnitine for preventing chemotherapy-related nerve damage [29]
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