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But because people on semaglutide or tirzepatide lose more weight in the first place, they all end up returning to baseline at approximately the same time, study senior researcher Dimitrios Koutoukidis of Oxford University told Reuters

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In this context, postbiotics are more plausibly positioned not as primary weight-loss interventions, but as nutritional strategies that may be continued after GLP-1based pharmacotherapy to support metabolic stability, mitigate weight regain, and preserve lean mass during the post-treatment phase ( From a clinical nutrition perspective, postbiotics should not be positioned as weight-loss agents, nor as substitutes for pharmacological GLP-1 receptor agonists