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Trends Biochem Sci 38:592602 Keszler A, Zhang Y, Hogg N (2010) Reaction between nitric oxide, glutathione, and oxygen in the presence and absence of protein: how are S-nitrosothiols formed

Glutathione is an important antioxidant which aids in protecting the body from oxidative stress, which results from the accumulation of reactive oxygen species

In that work, co-immunoprecipitation analysis showed reduced binding between caveolin-1 and eNOS, an interaction normally responsible for limiting eNOS activity

Without getting too deep into reduction-oxidation (redox) chemistry, a substance that can give away an electron and reduce its total number of electrons is called reducing