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Although GHRH-R couples with the G s protein, the addition of MK-0677 to rat primary cultured pituitary cells increased intracellular Ca 2+ levels, suggesting the existence of a second G protein-coupled receptor (GPCR) that couples with the G q protein, thereby promoting GH secretion through a pathway distinct from that of GHRH-R (Patchett et al., 1995)

Carnitine, which includes the compounds L-carnitine, acetyl-L-carnitine, and propionyl-L-carnitine is a natural substance derived from an amino acid

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Furthermore, the association of active histone codes H3K4Me3 and H3K9Ac was significantly reduced after NRF2 silencing (Fig