Vitiligo is characterised by depigmentation of patches of skin, resulting from the destruction of melanocytes (which produce the pigment, melanin) in the epidermis
IC50 was 34.19 M, 61.53 M in the senescent fibroblasts from keloid and normal skin, and 93.77 M, 104.6 M in non-senescent control fibroblasts from keloid and normal skin, respectively
Liraglutide 3 mg (Saxenda, FDA-approved for weight management), an earlier-generation daily GLP-1 injection, demonstrates similar gastrointestinal side effect patterns with diarrhea reported in approximately 21% of patients according to its FDA label
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