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"They'll feel better about the fact that they're on a medication if they go to a smaller dose, and, really, what we need to get to the root of is, let's make this patient feel whole from the beginning, that there's nothing wrong with using a medication." How 'microdosing' weight-loss medications can go wrong As with any prescribed medicine, weight-loss drugs should only be taken under the recommendation and supervision of a doctor

Like GLP-1, GIP helps regulate insulin and reduce appetite, but it also boosts fat metabolism and improves insulin sensitivity

Doctors may also prescribe it off-label to support weight loss and weight management

Note that an oral Wegovy pill was FDA-approved in December 2025, which may shift this dynamic for some patients