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Traditional GLP-1 drugs such as semaglutide are peptide-based molecules that can be broken down by stomach acid and digestive enzymes before they reach the bloodstream

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Retatrutide is administered as a once-weekly subcutaneous injection, similar in delivery to other agents in this drug class

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Ren B, Huang W, Akesson B, Ladenstein R (1997) The crystal structure of seleno-glutathione peroxidase from human plasma at 2.9 A resolution

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