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Research progress Support The animal experiments have achieved remarkable results: In the obese mouse model, after daily subcutaneous injection of AOD 9604 (250 g/kg) for 8 weeks, the body weight of the mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue significantly decreased, confirming its effectiveness in fat reduction
Any interpretation beyond laboratory research is speculative
Aapro MS, Bohlius J, Cameron DA, et al
Tirzepatide demonstrated approximately 5-fold lower affinity at the GLP-1 receptor compared to native GLP-1, and 20-fold lower potency in cellular signaling compared to semaglutide
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