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An 8-week double-blind randomized placebo-controlled trial in 62 patients with PWS demonstrated an improvement of hyperphagiaevaluated as behavior and severity scores by Dykens Hyperphagia Questionnaireafter Topiramate group versus placebo group, with no effects on BMI [95]

Clinical trials indicate that Orlistat, when used in conjunction with a reduced-calorie diet and increased physical activity, can lead to an average weight loss of approximately 5-8% of initial body weight over a year

Tanpa jumlah cystein yang bermakna, sel tidak cukup memproduksi Glutathione (GSH) dan tubuh berhadapan dengan tiga hal: oksidasi seluler yang menambah kemunduran secara umum dan proses penuaan, terkumpulnya racun-racun pada tubuh menyebabkan kerusakan lebih jauh dan sistem imunitas yang menurun membahayakan kita sehingga mudah terserang penyakit

doi: 10.1055/s-0035-1545344 38