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This happened back in the era of the DCCT, when patients had an intermittent worsening of retinopathy for the first year or two, but then had far better control of the retinopathy long-term. A question of heart versus eye

Exenatide was studied in Parkinsons disease : a 2017 Lancet trial showed that patients on weekly exenatide had a slight improvement in motor scores compared to placebo ( [142] )

While theres no evidence that expired semaglutide breaks down into something harmful, its impossible to predict how it might behave once its passed the expiration date manufacturers can only guarantee its safety and effectiveness up to the date on the label

Semaglutide also slows stomach emptying, which may help control appetite but can contribute to digestive side effects