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Factors that could cause or contribute to such differences include, but are not limited to: (1) Regulatory and governmental approvals: The approval process for pharmaceutical products is subject to extensive regulations and may involve uncertainties and delays

Dosing and measurement errors come first: the FDA describes adverse event reports involving mistakes in measurement and administration, some requiring hospitalization, and prescribing of doses beyond what the approved label supports higher single doses, more frequent administration, faster titration

As of November 2025, the average wait time for an initial Social Security Disability Insurance (SSDI) decision is 6.3 months, or roughly 193 days

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