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In a meta-analysis examining the efficacy of metformin treatment for GDM, it was found that the incidence of severe neonatal hypoglycemia was significantly reduced in the metformin-treated GDM group, potentially due to improved maternal glycemic management ( In summary, comprehensive care encompassing preconception, prenatal, and postnatal stages is essential for individuals with PCOS
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However, this phenomenon also confirms that the increase in high levels of plasma under previous obesity conditions can cause POMC neuron stimulation, which will further induce sympathetic activation
