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However, in different TMEs, especially in PC microenvironment, the effects of proportional and metabolic differences between MDSCs subsets on tumour cells as well as the effects of high glucose metabolism rate of MDSCs and their markers on the clinical prognosis of PC patients remain to be elucidated

Combining treatments may increase the risk of side effects or drug interactions

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The weight-loss results continued to the 48-week endpoint, with the 12 mg retatrutide group achieving a mean weight reduction of -24.2%, while the placebo group only saw a -2.1% change