switch from semaglutide to retatrutide vs. semaglutide: A head-to-head comparison switching from retatrutide to tirzepatide

132, 134-136 It is, therefore, important to ensure that all people with diabetes undergoing elective surgery, and specifically those requiring general anaesthesia or deep sedation, undergo preoperative evaluation if they are on GLP-1 receptor therapy, as recommendations regarding the cessation of these drugs are inconsistent and lack a sound evidence base

(PubMed) Carr AC, Frei B

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Another study supported that the stress of hyperglycemia induced the accumulation of advanced glycation end (AGE) products, which led to an increase in reactive oxygen species, the activation of inflammatory pathways and reduction of cardiac energy efficiency [42]