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GLP-1 receptor agonists act primarily by enhancing postprandial insulin secretion and suppressing glucagon release, leading to improved glycemic control ( Emerging evidence suggests that GLP-1 receptors are not confined to pancreatic islets but are also expressed in cardiomyocytes and vascular endothelial cells ( GLP-1 receptor activation induces vasodilation through various pathways

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& Muller, H

DSIP is studied in preclinical research on sleep biology, EEG slow-wave activity in rodent models, cortisol pathway research, and circadian regulation