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Inadequate response: If you feel Rybelsus is not effectively controlling your blood sugar or you have not achieved expected benefits, your doctor can review your treatment plan and consider alternatives

If you do not experience hunger suppression on lower doses, higher doses may be needed to reduce hunger

On tirzepatide, true thirst signals dehydration from fluid losses through the GI tract, increased urinary output from natriuresis, or inadequate fluid intake from reduced appetite

The FDAs general guidance on active pharmaceutical ingredients notes that a minor change in the salt form, ester or complex of a drug substance may result in significant changes in its properties