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Research has demonstrated that GLP-1RAs significantly inhibit the expression of MMP-2 and MMP-9 in the human ovarian cancer cell line SKOV-3 within a TNF--induced inflammatory microenvironment, while simultaneously upregulating the levels of their inhibitors, tissue inhibitors-1 (TIMP-1) and tissue inhibitors-2 (TIMP-2) [78, 87]
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otherwise, stomach acid and enzymes will break it down before it can be absorbed
Finally, synthesizing current research advances, existing challenges, and emerging trends, the review outlines future research directions aimed at enhancing the oxidative stress tolerance of microbial cell factories
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