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Clinically, glycine has been used as a component of total parenteral nutrition and has been investigated in various therapeutic contexts
It improved GSH/GSSG ratios and reduced inflammatory cytokines (IL-6, TNF-alpha), which may support overall metabolic health
A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes
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