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A separate meta-analysis that pooled results of trials in older adults with mild cognitive impairment found B-vitamin supplementation (6 to 24 months, depending on the trial) had no benefits on various cognitive parameters, including executive function, information processing speed, and episodic memory (90)

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At week 12, 71.4% and 74.7% of patients in the elinzanetant groups achieved at least a 50% reduction in VMS frequency the OASIS 1 and 2, respectively, compared with 42.0% and 48.3%, respectively, in the placebo groups