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[1] This superior bioavailability occurs because peptides utilize specialized transport systems -- small peptides can use multiple absorption pathways, including some that don't require cellular chaperones, while single amino acids rely on just one transport method that requires chaperone assistance
Pharmacovigilance study of GLP-1 receptor agonists for metabolic and nutritional adverse events
It is found that in the clinical follow-up studies of NAFLD patients, compared with the control group, hepatic fat content and ALT levels were not significantly reduced in Lira group and were associated with an increased incidence of gastrointestinal adverse events [118]
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