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This, in turn, boosts metabolic rate and activates a gene known as sirtuin-1 (SIRT1), also referred to as the "longevity gene." SIRT1 is involved in reducing the risk of various conditions such as diabetes, obesity, metabolic syndrome, atherosclerosis, cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer.

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GSTs are involved in multiple biological functions, including xenobiotic detoxification, clearance of oxidative stress products, protein transport, modulation of cell proliferation, and induction of the apoptosis signaling pathway [1]

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