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Altered glutathione (GSH, an important antioxidant and neuromodulator) and gamma-aminobutyric acid (GABA, a major inhibitory neurotransmitter) levels have been proposed as potential contributors to the biology underlying ASD

These effects are typically mild to moderate, dose-dependent, and tend to diminish with continued use and proper dose escalation

In prior clinical trials, CRWP was able to raise glutathione levels in those with obstructive lung disease ( In this study, we used a double-blind placebo-controlled design to explore the effectiveness of a 90-day intervention with a nutritional supplement containing CRWP in treating ASD core behavioral symptoms and elevating glutathione levels in 35-year-old preschool children with ASD