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When to stop and call your doctor If you develop severe abdominal pain (possible pancreatitis), severe allergic reaction, jaundice, or other serious symptoms
Although the effects of MMPs on tumor cells vary depending on the specific MMP subtype, tumor type, and patient characteristics, studies indicate that decreased MMP expression is strongly associated with the inhibition of tumor cell metastasis [85, 86]
[5] [6] Clinical trials demonstrated that approximately 91% of participants achieved at least 5% body weight reduction at the highest approved dose (15 mg), but this also means that some patients may not reach this threshold despite optimal dosing
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