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A common research model for inducing a rheumatoid-like arthritis involves injecting collagen type II subdermally or in connective tissues, which provokes autoimmune reactivity in susceptible animals
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It is generally safe, making it a reasonable trial for individuals with persistent symptoms despite other interventions
This gatekeeping approach means patients with A1C levels between 5.7% and 6.4%the clinical definition of prediabetesfall outside covered indications, even though clinical evidence supports early intervention
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