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This expansion reflects the market reality that tirzepatide has shown superior weight loss outcomes compared to semaglutide in head-to-head studies, averaging 20-25% total body weight reduction
It also slows gastric emptyingthe rate at which food leaves the stomachwhich contributes to prolonged satiety and helps patients consume fewer calories
In some species (rodents, pigs) there are also appreciable amounts of GLP-1 (7-37) which has similar activity to the 7-36 amide
Many individuals see noticeable changes in their weight within the first few months of starting treatment with semaglutide, especially when combined with a broader medical weight management plan that incorporates diet and exercise modifications
